While I generally think heavy lifting while avoiding failure is the best way to train, every once in a while I like to perform low weight high reps training to failure. This is primarily used for sarcoplasmic hypertrophy which results in muscle mass gains. Done strategically, training to failure can actually generate a nice “shrink-wrap effect” as well. However, over the long term, I think low weight high reps training is best left to bodybuilders. Sarcoplasmic Hypertrophy vs. Myofibrillar Hypertrophy Let’s get the technical stuff out of the way. Low weight high reps training to failure results in sarcoplasmic hypertrophy while high weight low reps training avoiding failure results in myofibrillar hypertrophy. So what’s the difference? Sarcoplasmic hypertrophy is characterized by bigger muscles. However, that volume is in the form of sarcoplasmic fluid. Fluids can’t contract so while sarcoplasmic hypertrophy results in muscles with mor...